Patients will need to stay in hospital for up to two weeks following heart transplant surgery. The main concern is the body rejecting the new heart and you will be constantly monitored and undergo regular biopsies so your physician can identify any damage. Many patients can return to doing vigorous activities but your physician will determine how long you need to wait on returning to work and exercise, which will depend on the healing period. You will be kept on medication and taught how to administer these (there may be side-effects).